Mary M. Lee, M.D.
Professor of Pediatrics and Cell & Developmental Biology
Chair, Department of Pediatrics
Co-Director of Clinical and Translational Research, Diabetes Center of Excellence
Chief, Pediatric Endocrine Division, Department of Pediatrics
Physician-in-Chief, UMass Memorial Children’s Medical Center
Expertise: Pediatric endocrinology, Reproductive development
Mary M. Lee, M.D. is Professor of Pediatrics and Cell & Developmental Biology and Chair, Department of Pediatrics,at the University of Massachusetts Medical School. She is also Physician-in-Chief for the UMass Memorial Children’s Medical Center. Her research focuses on understanding the role of Mullerian inhibiting substance in the testis and elucidating the hormonal and cellular interactions that are critical for testicular development. The research involves both clinical investigations and laboratory studies. The basic research efforts have focused on clarifying the paracrine and endocrine regulation of Leydig cell differentiation and on identifying the effects of persistent organic pollutants (endocrine disruptors, such as dioxins) on the developing male reproductive system. Areas of research interest: Biology and regulation of Mullerian inhibiting substance; Sexual differentiation and intersex disorders; Testicular differentiation and development (fetal and postnatal) of Leydig cells; the effects of environmental toxins on reproductive development; Gonadal toxicity of chemotherapy and radiation for childhood malignancies.